07/18/13: The Pure Probiotic Initiative: Strain authenticaiton: Genetics and beyond

The Pure Probiotic Initiative: Strain authenticaiton: Genetics and beyond By Kelly C. Heim, Ph.D. The Human Microbiome Project, a federally funded research program similar to the Human Genome Project, has identified more than 10,000 microbial species in the human body.1 Ongoing isolation and commercialization of probiotic organisms, together with strain-specific clinical research, continues to expand […]

Webinar: Keys to a restful night: Integrative strategies to optimize sleep onset and efficiency‡

June 19, 2013 Presented by James Greenblatt, M.D. Sleep is essential for overall health and quality of life. Neurotransmitters, the chemical messengers of the brain, play critical roles in regulating sleep onset, duration and quality. James Greenblatt, M.D. is an integrative psychiatrist who is the Founder and Medical Director of Comprehensive Psychiatric Resources, Inc., in […]

06/14/13: The Pure Probiotic Initiative: Probiotic Manufacturing: Temperature Control

The Pure Probiotic Initiative: Probiotic Manufacturing: Temperature Control By Kelly C. Heim, Ph.D. As living organisms, probiotics require nutrients and water to survive. However, during their residency in a capsule and bottle, these needs must go unrequited until the time they are consumed. To remain viable, the metabolic needs of probiotics must be negligible. Fortunately, […]

05/08/13: The Pure Probiotic Initiative: Probiotic Manufacturing: Moisture Control

The Pure Probiotic Initiative: Probiotic Manufacturing: Moisture Control By Kelly C. Heim, Ph.D. Probiotics are living cells with unique requirements for survival. Outside of the body, where nutrients and water are not available, these bacteria must remain in a metabolically dormant state to survive. During manufacturing, moisture and heat can disrupt this quiescence, decreasing stability. […]

04/11/13: The Pure Probiotic Initiative: Manufacturing: Timing is everything

The Pure Probiotic Initiative: Manufacturing: Timing is everything By Kelly C. Heim, Ph.D. Probiotics are living cells that are sensitive to any environment outside of the body. During manufacturing, systematic control of two familiar variables, temperature and moisture, helps to ensure survival. However, optimal protection demands attention to a third variable—timing. Reducing the time required […]

02/20/13: The Pure Probiotic Initiative: The triad of probiotic quality: Timing, temperature and moisture

The Pure Probiotic Initiative: The triad of probiotic quality: Timing, temperature and moisture By Kelly C. Heim, Ph.D. Probiotics are living organisms with unique sensitivities to their surroundings. Decades of research in microbiology have determined numerous predicates of their survival in different environments. Even with full GMP compliance, manufacturing poses many threats to probiotic survival […]